Upstream Process Development Webinar

Wednesday, September 16, 2015 - 12:00pm EST / 9:00am PST

Webinar Facilitator: Peter Russo

Shear Contributions to Cell Culture Performance and Product Recovery in ATF and TFF Perfusion Systems
Samantha Wang, PhD., Bioprocess Engineering, Boehringer Ingelheim

In perfusion systems, Alternating Flow Filtration systems are often attributed with better performance than Tangential Flow Filtration systems with regards to product recovery though not much is known about the mechanism behind this phenomenon. This study demonstrates that the pump shear, and not the alternating flow, is largely responsible for the performance differences between the two systems and offers a feasible TFF alternative to ATF systems.

Production of bispecific antibodies in “Knobs-into-Holes” using a cell-free expression system
Yiren (Joy) Xu, Senior Scientist, Sutro Biopharma, Inc

Cell free expression system (Xpress CF) enables expeditious evaluation of multiple knob-into-hole (KIH) bispecific scaffolds, providing valuable insights for KIH design to promote better assembly and expression.


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Key Information

  • All webinars are at 12 noon EST on Wednesdays
  • Cost is $190 per industrial registration, Academic coupon codes to waive the fee are available upon request (email BIOT@premierwebinars.com)
  • Webinars are provided on the WebEx Training Center Platform, be sure to clear access with your IT personnel before the date of the webinar

2015 Schedule

September 9th
Downstream Process Development

September 16th
Upstream Process Development

September 23rd
Biomolecular and Biophysical Processes and Peterson Awardee

September 30th
Emerging Technologies, and QbD

October 7th
Biosimilars and Follow on Biologics, Biofuels and Sustainable Energy


The American Chemical Society Biochemical Technology (BIOT) Division invites you to participate in the upcoming series of upcoming 60-minute web symposiums.

The Best of BIOT awards excellence in the annual meeting through the selection of ten presentations to be broadcast live in a series of webinars.



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